The prevalence of HBsAg in children presenting to the children's emergancy Hospital - Kha rtoum .

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Research type: Research Paper

Authors: Mekki, Muna Ismail El Misbah .

Abstract: A sero prevalence study was conducted at the children's Emergency Hospital - Khartoum, where 717 children aged 0-16 years of both sexes were randomly selected. The mean age was 5.6+4.6, with male to female ratio 1.1:1. 50 of the total population were seropositive for HBsAg thus the prevalence of HBsAg among the total study group was 7 percent, 50 controls matched by age and sex were selected randomly from the sero-ve study population for further analysis. The mean age of the HBsAg sero+ve cases was 6.7 + 4.1 yeres, with male to female ratio of 1.2:1. The highest prevalence of 20 percent was recorded in those aged less than 3 months suggesting vertical transmission as the mode of HBV infection. The significant predisposing factors found in this study were age less than 3 months, Kordofan as home of origin, refugees, illitracy of fathers, unavailability of latrines and scarification. Children aged 3 - 11 months and those originating from Khartoum were signigicantly less likely to be +ve for HBsAg. Hospitalization, jaundice, contact with jaundiced patient, operations, blood transfusion, circumcision, ear or nasal piercing and tattooing were all insignificant as predisposing factors in this study. Low serum total protien, albumen, and globulin were significantly more common among sero+ve cases.