The pattern and prevalence of urinary tract infection in Adult sudanese patients with chro nic renal failure .


Research type: Research Paper

Authors: Abdel Aziz, Mohamed Osman .

Abstract: Sudan is a large country with about 30 milion populations and an annual incidence of CRF of about 70-140 pmp/year. This study was conducted to evaluate the prevalence and pattern of UTI in adult Sudanese patients with CRF in the period from Dec. 1998 to May 1999. An equal number of patients were randomly selected from patients with CRF being treated by conservative management, PD, HD and renal transplant recipients, with a total number of 120 patients. The study revealed that the mean age of patients with CRF was 46.2 years, the male: female ratio 1.8:1 and 25 percent were in patients. The prevalence of significant bacteruria on urine culture was 30 percent and that of significant pyuria was 46.7 percent. The rate of infection was highest in the PD group compared to other groups (40 percent) and lowest in the transplant group (20 percent). The commonest organism isolated was E. COLI, accounting for 51.4 percent and predominating in the four groups. 94.6 percent of the isolated organisms were sensitive to one or more or the tested antibiotics and the best antibiotics with high sensitivity were augmentin, gentamycin and nalidixic acid, dipstick urinalysis showed high sensitivity, specificity and predictive values for the detection of haematuria, pyuria and bacteruria and can be used as a screening test to excude UTI in patients with CRF. There should be clear programs for the management of CRF in Sudan. Health education of the population about the hazards of UTI is mandatory. There should be an active search of UTI in patients with CRF followed b proper management of the detected cases.